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1

The characterization of mutant Bacillus subtilis adenylosuccinate lyases corresponding to severe human adenylosuccinate lyase deficiencies

Jennifer Brosius Palenchar, Jennifer M. Crocco, Roberta F. Colman

Journal:

Protein Science

Year:

2003

Language:

english

File:

PDF, 540 KB

english, 2003

2

Role of metal ions in reaction catalyzed by pig heart triphosphopyridine nucleotide-dependent isocitrate dehydrogenase. III. Frequency and temperature dependence of the proton relaxation rates of solvent and substrate interaction with isocitrate dehydrogenase-bound manganese(II)

Villafranca, Joseph J., Colman, Roberta F.

Journal:

Year:

1974

Language:

english

File:

PDF, 1.05 MB

english, 1974

3

Correction - The Role of Sulfhydryl Groups in the Catalytic Function of Isocitrate Dehydrogenase. I. Reaction with 5,5'-Dihiobis(2-nitrobenzoic acid)

Colman, Roberta

Journal:

Year:

1969

Language:

english

File:

PDF, 421 KB

english, 1969

4

A New Nonhydrolyzable Reactive cAMP Analog, (Sp)-Adenosine-3′,5′-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate Irreversibly Inactivates Human Platelet cGMP-Inhibited cAMP Phosphodiesterase

Su H. Hung, K.S. Madhusoodanan, James A. Beres, Robert L. Boyd, James L. Baldwin, Wei Zhang, Robert W. Colman, Roberta F. Colman

Journal:

Bioorganic Chemistry

Year:

2002

Language:

english

File:

PDF, 14.16 MB

english, 2002

5

Purification of nucleosidyl peptides by chromatography on dihydroxyboryl-substituted polyacrylamide and cellulose

Anjanayaki E. Annamalai, Pranab K. Pal, Roberta F. Colman

Journal:

Analytical Biochemistry

Year:

1979

Language:

english

File:

PDF, 602 KB

english, 1979

6

A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3′,5′-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A

Su H. Hung, Andy H. Liu, Robin A. Pixley, Penelope Francis, LaTeeka D. Williams, Christopher M. Matsko, Karine D. Barnes, Sharmila Sivendran, Roberta F. Colman, Robert W. Colman

Journal:

Bioorganic Chemistry

Year:

2008

Language:

english

File:

PDF, 776 KB

english, 2008

7

Chemical modification of enzymes: Critical evaluation of the graphical correlation between residual enzyme activity and number of groups modified

Evelyn Stevens, Roberta F. Colman

Journal:

Bulletin of Mathematical Biology

Year:

1980

Language:

english

File:

PDF, 656 KB

english, 1980

8

Cysteinyl peptides labeled by dibromobutanedione in reaction with rabbit muscle pyruvate kinase

Sara H. Vollmer, Roberta F. Colman

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 967 KB

english, 1992

9

Tyrosine 8 contributes to catalysis but is not required for activity of rat liver glutathione S-transferase, 1–1

Jibo Wang, Joseph J. Barycki, Roberta F. Colman

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 4.35 MB

english, 1996

10

Probing the active site of α-class rat liver glutathione S-transferases using affinity labeling by monobromobimane

Longqin Hu, Barbara L. Borleske, Roberta F. Colman

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 3.94 MB

english, 1997

11

GSTpi modulates JNK activity through a direct interaction with JNK substrate, ATF2

Anastasia F. Thévenin, Chati L. Zony, Brian J. Bahnson, Roberta F. Colman

Journal:

Protein Science

Year:

2011

Language:

english

File:

PDF, 621 KB

english, 2011

12

Determination by gel filtration of association constants for metal-nucleotide interaction

Roberta F. Colman

Journal:

Analytical Biochemistry

Year:

1972

Language:

english

File:

PDF, 375 KB

english, 1972

13

Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle

Hartong, Dyonne T, Dange, Mayura, McGee, Terri L, Berson, Eliot L, Dryja, Thaddeus P, Colman, Roberta F

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 308 KB

english, 2008

14

Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens

Sharmila Sivendran, Roberta F. Colman

Journal:

Protein Science

Year:

2008

Language:

english

File:

PDF, 639 KB

english, 2008

15

Delineation of xenobiotic substrate sites in rat glutathione S-transferase M1-1

Jennifer L. Hearne, Roberta F. Colman

Journal:

Protein Science

Year:

2005

Language:

english

File:

PDF, 570 KB

english, 2005

16

Contribution of the mu loop to the structure and function of rat glutathione transferase M1-1

Jennifer L. Hearne, Roberta F. Colman

Journal:

Protein Science

Year:

2006

Language:

english

File:

PDF, 396 KB

english, 2006

17

Important roles of hydroxylic amino acid residues in the function of Bacillus subtilis adenylosuccinate lyase

Mark L. Segall, Meghan A. Cashman, Roberta F. Colman

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 367 KB

english, 2007

18

Effect of Asp69 and Arg310 on the pK of His68, a key catalytic residue of adenylosuccinate lyase

Sharmila Sivendran, Mark L. Segall, Pumtiwitt C. Rancy, Roberta F. Colman

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 280 KB

english, 2007

19

Affinity cleavage at the divalent metal site of porcine NAD-specific isocitrate dehydrogenase

Yu-Chu Huang, Sambanthamurthy Soundar, Roberta F. Colman

Journal:

Protein Science

Year:

2000

Language:

english

File:

PDF, 262 KB

english, 2000

20

Synthesis, characterization, and reactions of 2′-, 3′-, and 5′-(2-bromoethyl)-AMP: Potential affinity labels for nucleotide binding sites in enzymes

Rodney A. Bednar, Roberta F. Colman

Journal:

The Protein Journal

Year:

1982

Language:

english

File:

PDF, 1.21 MB

english, 1982

21

Synthesis and characterization of iodopropyl derivatives of adenosine 3′,5′-cyclic-monophosphate: Potential affinity labels of cAMP binding sites in enzymes

Jessica E. Reimann, Paul G. Grant, Robert W. Colman, Roberta F. Colman

Journal:

The Protein Journal

Year:

1983

Language:

english

File:

PDF, 981 KB

english, 1983

22

Chemical modification of enzymes: Critical evaluation of the graphical correlation between residual enzyme activity and number of groups modified

Evelyn Stevens, Roberta F. Colman

Journal:

Bulletin of Mathematical Biology

Year:

1980

Language:

english

File:

PDF, 703 KB

english, 1980

23

Reaction of 5′-p-fluorosulfonylbenzoyl-1,N6-ethenoadenosine with histidine and cysteine residues in the active site of rabbit muscle pyruvate kinase

John M. Tomich, Roberta F. Colman

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1985

Language:

english

File:

PDF, 1.12 MB

english, 1985

24

Cadmium-113 and magnesium-25 NMR study of the divalent metal binding sites of isocitrate dehydrogenases from pig heart

Robert S. Ehrlich, Roberta F. Colman

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1995

Language:

english

File:

PDF, 662 KB

english, 1995

25

Chemical modification at subunit 1 of rat kidney Alpha class glutathione transferase with 2,3,5,6-tetrachloro-1,4-benzoquinone: Close structural connectivity between glutathione conjugation activity and non-substrate ligand binding

Siobhan M. O'Sullivan, Ronan M. McCarthy, Melissa A. Vargo, Roberta F. Colman, David Sheehan

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 363 KB

english, 2006

26

REGULATION OF ENZYMES BY SMALL MOLECULES

Roberta F. Colman

Journal:

Annals of the New York Academy of Sciences

Year:

1972

Language:

english

File:

PDF, 559 KB

english, 1972

27

Role of Manganous Ion in the Kinetics of Pig-Heart NAD-Specific Isocitrate Dehydrogenase

Phyllis F. COHEN, Roberta F. COLMAN

Journal:

Year:

1974

Language:

english

File:

PDF, 1020 KB

english, 1974

28

The Importance of Arginine Residues in the Catalytic and Regulatory Functions of Bovine-Liver Glutamate Dehydrogenase

Pranab K PAL, Roberta F. COLMAN

Journal:

Year:

1976

Language:

english

File:

PDF, 656 KB

english, 1976

29

Histidine in the Nucleotide-Binding Site of NADP-Linked Isocitrate Dehydrogenase from Pig Heart

Robert S. EHRLICH, Roberta F. COLMAN

Journal:

Year:

1978

Language:

english

File:

PDF, 1.21 MB

english, 1978

30

Distance between the substrate and regulatory reduced coenzyme binding sites of bovine liver glutamate dehydrogenase by resonance energy transfer

Richard H. LARK, Roberta F. COLMAN

Journal:

Year:

1990

Language:

english

File:

PDF, 842 KB

english, 1990

31

Platelet Activation by 2-(4-bromo-2,3-dioxobutylthio)Adenosine 5′-Diphosphate is Mediated by Its Binding to A Putative ADP Receptor, Aggregin

Rajinder N. Puri, Roberta F. Colman, Robert W. Colman

Journal:

Year:

1996

Language:

english

File:

PDF, 1.08 MB

english, 1996

32

Modulation of Platelet Responses by 2-[3-(Bromo-2-oxopropylthio)]adenosine-5′-diphosphate Involves Its Binding to as Well as Covalent Modification of an ADP-Receptor, Aggregin

Rajinder N. Puri, Roberta F. Colman, Robert W. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 211 KB

english, 1997

33

Identification of the Nonsubstrate Steroid Binding Site of Rat Liver GlutathioneS-Transferase, Isozyme 1-1, by the Steroid Affinity Label, 3β-(Iodoacetoxy)dehydroisoandrosterone

Joseph J. Barycki, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 685 KB

english, 1997

34

Identification of the Subunits and Target Peptides of Pig Heart NAD-Specific Isocitrate Dehydrogenase Modified by the Affinity Label 8-(4-Bromo-2,3-dioxobutylthio)NAD

Yu-Chu Huang, Ajay Kumar, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 299 KB

english, 1997

35

Affinity Labeling of Pig Lung GlutathioneS-Transferase Pi by 4-(Fluorosulfonyl)benzoic Acid

Nicole E. Pettigrew, Michele Moyer-Myers, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 100 KB

english, 1999

36

8-(4-Bromo-2,3-dioxobutylthio)guanosine 5′-Triphosphate: A New Affinity Label for Purine Nucleotide Sites in Proteins

Peychii Lee, Andrea Gorrell, Herbert J. Fromm, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 110 KB

english, 1999

37

Heterodimers of Glutathione S-Transferase Can Form between Isoenzyme Classes pi and mu

Nicole E. Pettigrew, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

38

Expression of Pig Heart Mitochondrial NADP-Dependent Isocitrate Dehydrogenase inEscherichia coli

Sambanthamurthy Soundar, Gary T. Jennings, Lee Mcalister-Henn, Roberta F. Colman

Journal:

Protein Expression and Purification

Year:

1996

Language:

english

File:

PDF, 200 KB

english, 1996

39

Cysteine in the manganous-isocitrate binding site of pig heart TPN-specific isocitrate dehydrogenase: II. Identification of a critical cysteine-containing tryptic peptide derived from the thiocyano enzyme

Roy A. Johanson, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 2.84 MB

english, 1981

40

Cysteine in the manganous-isocitrate binding site of pig heart TPN-specific isocitrate dehydrogenase: I. Kinetics of chemical modification and properties of thiocyano enzyme

Roy A. Johanson, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 1.18 MB

english, 1981

41

Evidence for distinguishable sites of attack in the reactions of 5′-p-fluorosulfonylbenzoyl adenosine and 5′-p-fluorosulfonylbenzoyl guanosine with rabbit muscle pyruvate kinase

Anjanayaki E. Annamalai, John M. Tomich, Maria T. Mas, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 867 KB

english, 1982

42

Activity associated with individual subunits of pig heart NAD-specific isocitrate dehydrogenase

Selma Hayman, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 2.07 MB

english, 1982

43

Distinction between glycoprotein IIIa and the 100-kDa membrane protein (aggrogin) mediating ADP-induced platelet activation

Robert W. Colman, William R. Figures, Qi-Xia Wu, Si-Yin Chung, Thomas A. Morinelli, George P. Tuszynski, Roberta F. Colman, Stefan Niewiarowski

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 1.19 MB

english, 1988

44

Modification of NAD-dependent isocitrate dehydrogenase by the 2′,3′-dialdehyde derivatives of NAD, NADH, NADP, and NADPH

Amy Saha, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 1.13 MB

english, 1988

45

Identification of histidyl peptide labeled by 2-(4-bromo-2,3-dioxobutylthio)adenosine 5′-monophosphate in an ADP regulatory site of glutamate dehydrogenase

Surendra P. Batra, Richard H. Lark, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 853 KB

english, 1989

46

Thrombin-induced platelet aggregation involves an indirect proteolytic cleavage of aggregin by calpain

Rajinder N. Puri, Fengxin Zhou, Harlan Bradford, Chang-Jun Hu, Roberta F. Colman, Robert W. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 1.40 MB

english, 1989

47

5′-p-(Fluorosulfonyl)benzoyl-8-azidoadenosine: A new bifunctional affinity label for nucleotide binding sites in proteins

Kenneth E. Dombrowski, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1989

Language:

english

File:

PDF, 710 KB

english, 1989

48

Reaction of the nucleotide analogue 2-[(4-bromo-2,3-dioxobutyl) thio]adenosine 2′,5′-bisphosphate at the coenzyme site of wild-type and mutant NADP+-specific glutamate dehydrogenases from Salmonella typhimurium

Lorraine Haeffner-Gormley, Zengdao Chen, Howard Zalkin, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 1.28 MB

english, 1992

49

Inactivation of pig heart NADP-specific isocitrate dehydrogenase by two affinity reagents is due to reaction with a cysteine not essential for function

Gerald E. Smyth, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 711 KB

english, 1992

50

Identification of Tyr115 labeled by S-(4-bromo-2,3-dioxobutyl)glutathione in the hydrophobic substrate binding site of glutathione S-transferase, isoenzyme 3-3

Rose Monica Katusz, Bartholomew Bono, Roberta F. Colman

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 1.34 MB

english, 1992